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En Novel Coronavirus Antigen test oppdager viruset ved de spesifikke piggete proteinene (i.e. Antigenene) på virusets overflate, for å identifisere eksistensen av viruses i prøven.

En Antibody test oppdager molekylene (i.e. Antibodies) vi mennesker produserer etter å ha blitt smittet med viruset. Antibodies blir ikke produsert før flere dager etter smitte og blir oftest i blodet i en periode etter at personen blir frisk. Det er to typer, IgM Antibodies som i utgangspunktet blir produsert for å kjempe infeksjonen, men som forsvinner etter flere uker, og IgG Antibodies som blir produsert senere i syklusen og som generelt forblir i kroppen mye lengre. Derfor, mens Antibody test har veldig begrenset bruk innen diagnose av nye COVID-19 tilfeller, er den viktig for å indikere potensiell immunitet. Derimot, akkurat nå, er det ukjent hvor lenge den type immunitet vil vare.

En Antigen test er basert på en immun reaksjon, mens en nukleinsyre test er basert på genetisk informasjon. Derfor, kan en Antigen test gi resultatet raskere enn en nukleinsyre test. (15 minutter sammenlignet med 4 timer). Kostnaden for hurtigheten er sensitivitet. En Antigen test er ikke like sensitiv som en nukleinsyre test. Nukleinsyre testen kan oppdage en mikroskopisk mengde av SARS-CoV-2 viruset på grunn av sin sensitivitet brukt i forsterkninsprosessen av virus genetisk informasjon. Det er derfor en PCR test tar flere timer og er kapabel til å forårsake aerosolforurensning.

It does not require any laboratory processing and hence are suitable for large scale general screening of the population. In North America & Europe all licensed Rapid-test Antigen products are currently required to only be used by qualified professionals. However, it appears likely that Antigen tests for home use, without professional supervision, will eventually be permitted.However, if the human body contains only a very low viral load, with no obvious clinical symptoms, then an Antigen test is likely to give a negative result, thus a false negative. Helpfully, the ability of people with a low viral load to spread the virus is correspondingly lower than heavily infected patients. The Antigen test is suitable as a triaging or screening test to determine whether or not a slow but accurate nucleic acid test should be obtained.An Antigen test will be efficient in quickly identifying people with high levels of infection, those who are most likely to infect others, and distinguishing those people from others with, for example, seasonal influenza. Therefore, Antigen tests can be effective in helping to limit the spread of the pandemic, by identifying those who are most likely to spread the disease and isolating them from others.

As an Antigen test detects the virus itself sample collection is very important because the virus is only present in some areas of the body. This is different from the collection of a blood sample for an Antibody test when we may expect the Antibodies to be present throughout the patient’s venous blood, although likely to be less present in capillary blood. Accordingly, we recommend the use of a sputum sample, because sputum is a secretion from the respiratory tract where the SARS-CoV-2 virus clusters the most.Hence using sputum provides a more certain method of successfully collecting a reasonable quantity of the virus in the sample, if it is present when compared with the back of the throat nasopharyngeal sample. Because the virus is unevenly distributed on the nasopharyngeal mucosa, it is not certain that a successful sample will be obtained from this area which may lead to a false-negative result. It is much more difficult and requires both expertise and some luck to obtain a truly representative sample from the back of the throat. Therefore, the nasopharyngeal sample accuracy will be lower than that of sputum. Studies have shown that after people are infected, the viruses survive, and thus can be detected, in the digestive tract, especially in the intestinal stool. Therefore, if convenient (e.g. in the hospital or at home), a stool sample is another option for testing; Saliva samples mixed with sputum also have a certain probability of detection, although the amount of virus contained is lower than pure sputum.

Sputum is the mucus that is coughed up from the lower airways (the trachea and bronchi). When taking a sample one should avoid its contamination / dilution with saliva so far as possible. Saliva (commonly referred to as spit) is an extracellular fluid produced and secreted by salivary glands in the mouth.

The WHO has always been a supporter of Antigen testing. Experts point out that compared with conducting an accurate test every two weeks, conducting a relatively insensitive quick test twice a week can more effectively contain the spread of SARS-CoV-2. The reason is that it is more helpful in containing the spread of the infection where the focus is on identifying those who are likely to spread SARS-CoV-2, rather than locating anyone who is infected in any way with SARS-CoV-2 – but with a low infection much less likely to spread it.

Den første LETT Å BRUKE COVID-19-tester er nå CE-sertifiserte og godkjent for distribusjon og salg over hele Europa.

The HealthOx Biotech Ltd Antigen and Antibody tests are certified in the UK, Europe and Asia, and ready for medical use. They are approved by the MHRA and BSI and have earned the UK’s British Standards Institution (BSI) mark and the EU’s CE Certificate of Compliance.

All of our test kits can be ordered online via our website for delivery within 2-5 days. We also cater for telephone orders. Please contact hi@healthoxbiotech.com